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- Rhoden EL, Morgentaler A. Risks of testosterone-replacement therapy and proposals for monitoring.
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Discover why industry-leading companies across the globe love our data. IPinfo’s correct insights fuel use cases from cybersecurity, knowledge enrichment, web personalization, and far more. Effects of testosterone on coronary vasomotor regulation in males with coronary coronary heart illness. Manifestation of severe coronary coronary heart disease after anabolic drug abuse. Relationship between endogenous sex hormone ranges, lipoproteins and coronary atherosclerosis in men undergoing coronary angiography. Basaria S, Dobs AS. Risks versus advantages of testosterone remedy in elderly males.
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We report a case of an acute ST-segment elevation myocardial infarction in a affected person with conventional cardiac threat factors using supraphysiologic doses of supplemental, intramuscular testosterone. In addition, this affected person also had polycythemia, likely secondary to high-dose testosterone. The affected person underwent profitable percutaneous intervention of the best coronary artery. Physicians and sufferers ought to concentrate on the scientific consequences of anabolic steroid abuse. Development of an atheromatous plaque perpetuates endothelial dysfunction and promotes platelet aggregation and intracoronary thrombus formation (Ajayi et al 1995; Nieminen et al 1996). Moreover, a part of endothelial dysfunction has been proposed, which may contribute to abnormal vessel reactivity.
Case Report
In addition, the information obtainable within the literature doesn’t account for the steroid kind or dose, as neither may be recognized. Patients additionally may be taking concomitant stimulants, corresponding to ephedra, which can confound information and the potential for opposed events. It is likely that the frequency of cardiac events is underreported in the medical literature. Supraphysiologic doses of anabolic-androgenic steroids , which embody more than 30 natural and synthetic derivatives of testosterone, might trigger a large spectrum of medical sequalae.
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Anabolic Steroids, Acute Myocardial Infarction And Polycythemia: A Case Report And Review Of The Literature
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